Sasai H, Kikkawa N, Numata N, Sakai H, Funahashi S, Kawahara T
Gan To Kagaku Ryoho. 1982 Feb;9(2):269-74.
The changes of host immunity during the cancer treatment were studied in 27 patients with large bowel cancer. As the result, compared with preoperative status, increasing tendency of serum IgG, IgA levels, normalization of T cell per cent and remarkably lowered CH50 level were found postoperatively. However, in the patients treated with immunochemotherapy, no definite changes were found during the treatment. It was suggested that the CH50 level might have close relation to the curativity or the prognosis in these operative cases.
对27例大肠癌患者在癌症治疗期间宿主免疫的变化进行了研究。结果发现,与术前状态相比,术后血清IgG、IgA水平呈上升趋势,T细胞百分比恢复正常,CH50水平显著降低。然而,在接受免疫化疗的患者中,治疗期间未发现明确变化。提示CH50水平可能与这些手术病例的治愈率或预后密切相关。