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[Juvenile Duhring's disease. Apropos of 7 cases].

作者信息

Fernando Giménez M, Guillermo Crespi H, Martí R, Ferrando J

出版信息

Med Cutan Ibero Lat Am. 1982;10(6):369-78.

PMID:6764239
Abstract

Chronic non hereditary subepidermal blistering diseases are in childhood and present mainly problems on its clinical and histological diagnosis. Immunopathologic, immunogenetic and ultrastructural studies play a definitive role in the classification of this group of entities. In this paper we report and comment seven children affected of dermatitis herpetiformis. The clinical diagnosis was assessed by direct immunofluorescence studies of the skin, which showed granular Ig A deposits at the MBZ. In five out of our seven patients we were able to demonstrate by clinic and laboratory malabsorption syndrome. A bibliographic review of the subject is carried out, stressing specially the differential aspects with other subepidermal blistering disease of the childhood (i. e. bullous pemphigoid and chronic benign blistering disease of the childhood) as well as some other acute and chronic infantile blistering entities.

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