Iber F L, Blass J P, Brin M, Leevy C M
Am J Clin Nutr. 1982 Nov;36(5 Suppl):1067-82. doi: 10.1093/ajcn/36.5.1067.
Status of thiamin in the elderly North American population is reviewed. Most Americans eat sufficient thiamin but about 5% of those over 60 yr old show impaired thiamin status. This is more marked in the poor, those confined in institutions, or those with illness. Thiamin responsive heart disease and Wernicke Korsakoff CNS syndromes occur in the elderly but there is no increased prevalence. Minor heart or neurological syndromes related to thiamin deficiency cannot be identified. The Recommended Dietary Allowance of thiamin provides at least 50% excess thiamin for those over 60 yr old--this amount is adequate. There is no known toxicity for thiamin.
本文综述了北美老年人群中硫胺素的状况。大多数美国人摄入的硫胺素充足，但60岁以上人群中约5%的人硫胺素状况不佳。这在贫困人口、机构收容人员或患病者中更为明显。硫胺素反应性心脏病和韦尼克-科尔萨科夫中枢神经系统综合征在老年人中出现，但患病率并未增加。与硫胺素缺乏相关的轻微心脏或神经综合征无法识别。硫胺素的推荐膳食摄入量为60岁以上人群提供了至少50%的过量硫胺素——这个量是足够的。硫胺素没有已知的毒性。
