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[甲型肝炎病毒IgM类抗体在病毒性肝炎鉴别诊断中的应用]

[IgM class antibodies against hepatitis A viruses in the differentiation of viral hepatitis].

作者信息

Zivanović-Marinković V, Stanković D, Parabucki S, Lazarov A, Marinković V, Krstić L, Letica Z

出版信息

Zb Vojnomed Akad. 1982;24:24-7.

PMID:6765185
Abstract

The sera of 64 patients with acute viral hepatitis which were previously HbsAG negative by rPHA were tested by RIA methods for the presence of HBsAG and anti-HBc, by EIA method for HBc and anti-HBc and also by RIA method for the presence of IgM antibodies against hepatitis A virus. The pairs of sera were tested also for the presence of antibodies against cytomegalovirus and EB viruses. Of the total of 64 patients, markers of fresh HB viral infection were proved in 5 patients, sera positive to IgM antibodies to hepatitis A virus were found in 51 and no positive tests to any of the tested viruses were found in 8. The authors consider that they belonged to "non-A, non-B" viral hepatitis.

摘要

用放射免疫分析法(RIA)检测64例急性病毒性肝炎患者的血清中乙型肝炎表面抗原(HBsAG)和抗乙型肝炎核心抗体(anti-HBc),这些患者之前反向被动血凝试验(rPHA)检测HBsAG为阴性;用酶免疫分析法(EIA)检测乙型肝炎核心抗原(HBc)和抗-HBc;还用RIA法检测抗甲型肝炎病毒IgM抗体。同时检测血清对巨细胞病毒和EB病毒抗体的存在情况。64例患者中,5例证实有近期HB病毒感染标志物,51例血清抗甲型肝炎病毒IgM抗体呈阳性,8例对任何检测病毒均无阳性结果。作者认为他们属于“非甲非乙”型病毒性肝炎。

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