Khokher M A, Dandona P
Diabetes Care. 1982 Nov-Dec;5 Suppl 2:102-3. doi: 10.2337/diacare.5.2.s102.
To assess whether human insulin (recombinant DNA) is superior to porcine insulin, we compared the biologic effect of these two insulin preparations on rat and human adipocyte lipogenesis in vitro. The biologic potency of these two insulin preparations was similar on both human and rat adipocytes. Iodination of human and porcine insulin with 125I at A14 position led to a significant but similar loss of potency of both insulin preparations.
为评估人胰岛素（重组DNA）是否优于猪胰岛素，我们在体外比较了这两种胰岛素制剂对大鼠和人脂肪细胞脂肪生成的生物学效应。这两种胰岛素制剂对人和大鼠脂肪细胞的生物学效力相似。在A14位用125I对人胰岛素和猪胰岛素进行碘化导致两种胰岛素制剂的效力均出现显著但相似的降低。
