Curtis A M, Ravin C E, Collier P E, Putman C E, McLoud T, Greenspan R H
AJR Am J Roentgenol. 1980 Feb;134(2):253-5. doi: 10.2214/ajr.134.2.253.
Until now no large prospective study has been made to evaluate the efficacy of full lung tomography in detection of pulmonary metastases from carcinoma of the breast in the presence of a negative chest radiograph. In the current study, 144 patients with proven breast carcinoma and a negative chest radiograph underwent full lung tomography. Nodules were demonstrated in three patients and, in two of them, presumably reflected metastatic disease. Both patients had advanced extrapulmonary metastatic disease at the time of full lung tomography and in neither case did a change in therapy result. One presumed false-positive observation was also made. Because of the low propensity for carcinoma of the breast to metastasize to the lungs, full chest tomography does not appear warranted as a screening procedure in these patients.
迄今为止，尚无大型前瞻性研究评估在胸部X线片呈阴性的情况下，全肺断层扫描在检测乳腺癌肺转移方面的疗效。在本研究中，144例经证实患有乳腺癌且胸部X线片呈阴性的患者接受了全肺断层扫描。3例患者显示有结节，其中2例可能提示为转移性疾病。这2例患者在进行全肺断层扫描时均已有晚期肺外转移，且治疗均未改变。还出现了1例假阳性结果。由于乳腺癌转移至肺部的倾向较低，全胸断层扫描似乎不适合作为这些患者的筛查手段。
