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[对辐射敏感的果蝇品系。II. 控制诱变敏感性的2号突变染色体基因的鉴定]

[Radiosensitive Drosophila lines. II. Identification of the mutant chromosome 2 genes that control mutagen sensitivity].

作者信息

Khromykh Iu M, Zakharov I A

出版信息

Genetika. 1981;17(4):658-66.

PMID:6785152
Abstract

Genetic control of somatic mutagen sensitivity was studied in a strain of Drosophila melanogaster containing mutations in the second chromosome. The method used allowed to identify the determinants of different kind of sensitivity in the same experiment. It has been shown that the second chromosome of the strain analysed carries two independent mutations, one of them determining supersensitivity of Drosophila larvae to ionizing radiation, the other--to methyl methane-sulfonate. Mutant loci have been located at 59,9 +/- 1,1 and 73,8 +/- 2,5 units of the chromosome genetic map. They have been called rad(2)201G1 and mus(2)201G1, respectively.

摘要

在一个第二染色体含有突变的黑腹果蝇品系中,研究了体细胞诱变敏感性的遗传控制。所使用的方法能够在同一实验中鉴定出不同类型敏感性的决定因素。结果表明,所分析品系的第二染色体携带两个独立的突变,其中一个决定果蝇幼虫对电离辐射的超敏感性,另一个决定对甲基磺酸甲酯的超敏感性。突变位点分别位于染色体遗传图谱的59.9±1.1和73.8±2.5单位处。它们分别被称为rad(2)201G1和mus(2)201G1。

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