Halsey J F, Johnson B H, Cebra J J
J Exp Med. 1980 Mar 1;151(3):767-72. doi: 10.1084/jem.151.3.767.
Oligomeric, J-chain-containing immunoglobulins were observed to be transferred selectively from serum into colostrum. These studies suggest that, in the case of the mammary gland secretion, a significant role for extraglandular synthesis of IgA merits consideration. Thus, for example, colostrum may contain antibodies synthesized locally as well as antibodies synthesized in the much larger lymphoid tissues such as the gut lamina propria.
观察到含J链的寡聚免疫球蛋白可选择性地从血清转移至初乳中。这些研究表明,就乳腺分泌而言,值得考虑腺外合成IgA的重要作用。因此,例如,初乳可能既含有在局部合成的抗体,也含有在诸如肠道固有层等更大的淋巴组织中合成的抗体。