癫痫大发作后的血清催乳素和皮质醇浓度。
Serum prolactin and cortisol concentrations after grand mal seizures.
作者信息
Abbott R J, Browning M C, Davidson D L
出版信息
J Neurol Neurosurg Psychiatry. 1980 Feb;43(2):163-7. doi: 10.1136/jnnp.43.2.163.
Abstract
Serial serum prolactin and cortisol levels were measured in five patients after a grand mal seizure and in four volunteers with simulated seizures. Single levels were measured after a witnessed seizure in 26 patients and in a matched control group. Significant increase in both prolactin and cortisol levels occurred after seizures. The change in cortisol level may reflect a non-specific stress response, but the increase in prolactin levels could not be accounted for on this basis, and probably indicates an alteration in hypothalamic neurotransmitter activity during the seizure. These findings may have clinical value in the diagnosis of epilepsy.
摘要
对5例癫痫大发作后的患者以及4例模拟癫痫发作的志愿者测定了血清催乳素和皮质醇的系列水平。对26例有目击发作的患者及其配对对照组测定了单次水平。癫痫发作后催乳素和皮质醇水平均显著升高。皮质醇水平的变化可能反映了一种非特异性应激反应，但催乳素水平的升高无法基于此得到解释，可能表明癫痫发作期间下丘脑神经递质活性发生了改变。这些发现可能在癫痫的诊断中具有临床价值。
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Some observations on the determination of cortisol in human plasma by radioimmunoassay using antisera against cortisol-3-BSA.关于使用抗皮质醇-3-牛血清白蛋白抗血清通过放射免疫分析法测定人血浆中皮质醇的一些观察结果。
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