Myerberg D Z, York C, Chaplin E R, Gregory G A
Pediatrics. 1980 Mar;65(3):473-6.
After creating "fontanelles" in infant rhesus monkeys, we measured intracranial pressure of these monkeys directly with an indwelling cannula and indirectly with a Ladd 1700 sensor. Values obtained with the Ladd sensor placed over the shaven fontanelle closely approximate directly measured pressure in acute experiments in these animals and in human cadavers. Application of the device is simple and application pressure need not always be the same for multiple determinations. The response time is 1.6 cm H2O/sec, which is adequate to record changes in intracranial pressure caused by changes in the partial pressure of CO2 in arterial blood.
在幼年恒河猴身上制造“囟门”后，我们用留置套管直接测量这些猴子的颅内压，并用Ladd 1700传感器间接测量。在这些动物和人类尸体的急性实验中，将Ladd传感器置于剃毛后的囟门上所获得的值与直接测量的压力非常接近。该设备使用简单，多次测量时施加压力不必始终相同。响应时间为1.6厘米水柱/秒，足以记录动脉血中二氧化碳分压变化引起的颅内压变化。
