Salzman E W, Davies G C
Ann Surg. 1980 Feb;191(2):207-18. doi: 10.1097/00000658-198002000-00013.
The rapidly expanding literature regarding prevention of venous thromboembolism is confusing and contradictory, but, when analysed in the aggregate, the collective experience permits a judgment about the relative efficacy of different prophylactic regimens in specific patient populations, who vary in the risk factors predisposing them to thromboembolism. The dollar cost of the several approaches to prevention and their consequences should also be a matter of concern. Efficacy and dollar cost together determine cost effectiveness, which provides a practical guide to selection of the prophylactic approach appropriate to an individual patient.
关于静脉血栓栓塞预防的文献迅速增加,令人困惑且相互矛盾,但总体分析时,这些经验可对不同预防方案在特定患者群体中的相对疗效做出判断,这些患者群体因易发生血栓栓塞的危险因素不同而存在差异。几种预防方法的成本及其后果也应引起关注。疗效和成本共同决定成本效益,这为选择适合个体患者的预防方法提供了实用指南。