Roberts M M, Greaves M F
Eur J Immunol. 1980 Jan;10(1):46-52. doi: 10.1002/eji.1830100110.
An antiserum raised against human fetal and childhood thymocytes (anti-Thy) and absorbed with peripheral lymphocytes (tonsil) detected an antigen(s) shared by thymocytes, T cell-acute leukemias, activated peripheral T cells and a subset of peripheral T cells. The antigen was expressed by the negative circulating T cell subset after mitogen activation of that separated population. The antigen was shown to be separate from the E rosette receptor, another anti-T cell serum detected antigen, and beta 2-microglobulin; its expression was not related to a particular phase of the cell cycle. The results suggest that the antigen is expressed by T cells only under certain maturational and proliferative conditions.
一种针对人类胎儿和儿童胸腺细胞产生的抗血清（抗-Thy），经外周淋巴细胞（扁桃体）吸收后，检测到一种胸腺细胞、T细胞急性白血病、活化外周T细胞以及外周T细胞亚群所共有的抗原。该抗原在丝裂原激活分离出的循环T细胞阴性亚群后表达。已证明该抗原与E花环受体、另一种抗T细胞血清检测到的抗原以及β2-微球蛋白不同；其表达与细胞周期的特定阶段无关。结果表明，该抗原仅在某些成熟和增殖条件下由T细胞表达。
