Lennerstrand G, Hanson J
Acta Physiol Scand. 1978 Jun;103(2):144-53. doi: 10.1111/j.1748-1716.1978.tb06201.x.
The changes with postnatal age in post-tetanic potentiation (PTP) and fatigue of the inferior oblique muscle have been studied in the cat. PTP of the twitch amplitude increased steadily with age up to 20 weeks after birth. Twitch contraction time (ct) and half relaxation time (hrt) was not significantly changed. The potentiation of the tetanic response also became more prominent with age. The young muscles (10 weeks and below) were slightly more susceptible to fatigue than older muscles, but recovery was rapid in muscles of all ages. Intensive stimulation induced post-tetanic depression of twitch responses in muscles older than 1 week, but none in the muscles of new-born cats. Ct and hrt were greatly prolonged in muscles above six weeks of age. In these muscles, but never in the very youngest, repetitive firing could be observed in response to post-tetanic single nerve stimulation. The results are compared with those obtained in similar experiments on hind-limb muscles by other workers. They further support the idea, raised in a previous paper, that slow eye muscle fibres develop quicker and reach maturity earlier than fast fibres.
在猫身上研究了产后年龄对下斜肌强直后增强（PTP）和疲劳的影响。出生后至20周，抽搐幅度的PTP随年龄稳步增加。抽搐收缩时间（ct）和半松弛时间（hrt）无显著变化。强直反应的增强也随年龄变得更显著。年轻肌肉（10周及以下）比年长肌肉稍易疲劳，但各年龄段肌肉恢复都很快。1周以上肌肉经强烈刺激后会出现抽搐反应的强直后抑制，新生猫肌肉则无此现象。六周龄以上肌肉的ct和hrt大幅延长。在这些肌肉中，而非最年幼的肌肉中，可观察到强直后单神经刺激引发的重复放电。将这些结果与其他研究者在后肢肌肉类似实验中获得的结果进行了比较。它们进一步支持了前一篇论文中提出的观点，即慢眼肌纤维比快纤维发育更快且更早成熟。
