Mörl H, Diehm C, Zimmermann R, Schöffel G, Walter E
MMW Munch Med Wochenschr. 1980 Feb 22;122(8):277-80.
We report the results of a pilot study to evaluate the therapeutical efficiency of Benzarone in a time span of four weeks in 11 male patients with intermittent claudication. Numerous experimental data indicate that there was a statistically significant increase of painless walking distance and a statistically significant decrease of plasma uric acid, cholesterol and triglycerides. Coagulation analyses furthermore show an increase of the factor VIII activity and the plasminogen levels. For the first time, positive results were shown with Benzarone in patients with intermittent claudication.
我们报告了一项初步研究的结果,该研究旨在评估苯扎隆对11名间歇性跛行男性患者在四周时间内的治疗效果。大量实验数据表明,无痛行走距离有统计学意义的增加,血浆尿酸、胆固醇和甘油三酯有统计学意义的降低。凝血分析还显示因子VIII活性和纤溶酶原水平增加。首次在间歇性跛行患者中使用苯扎隆显示出阳性结果。