Lom-Orta H, Diaz-Jouanen E, Alarcon-Segovia D
J Rheumatol. 1980 Mar-Apr;7(2):178-82.
We report 5 patients with systemic lupus erythematosus (SLE) who presented with severe protein-caloric malnutrition that overshadowed the clinical picture of SLE. All 5 patients had severe anemia, extreme lymphopenia and hypoalbuminemia, but all 5 also had striking hypergammaglobulinemia with high titers of autoantibodies. These patients show that SLE may occur in subjects with endemic malnutrition and suggest that the production of autoantibodies in SLE patients overrules the requirements for the production of other proteins.
我们报告了5例系统性红斑狼疮（SLE）患者，他们出现了严重的蛋白质-热量营养不良，这掩盖了SLE的临床表现。所有5例患者均有严重贫血、极度淋巴细胞减少和低白蛋白血症，但所有5例患者也都有显著的高丙种球蛋白血症和高滴度自身抗体。这些患者表明，SLE可能发生在地方性营养不良的患者中，并提示SLE患者自身抗体的产生优先于其他蛋白质的产生需求。
