Linco S J, Grohmann G S
Med J Aust. 1980 Mar 8;1(5):211-3.
Approximately 60 persons attended a Christmas dinner, at a Darwin hotel, where oysters were served au natural as part of the menu. Twenty-five of the 28 persons who ate oysters developed symptoms of food poisoning--an attack rate of 89%. Of the 60 persons attending the dinner 44 were investigated. The incubation period and duration of illness were about 36 hours. Diarrhoea occurred in 100% of patients, with colic and nausea in 88% and 80% respectively. Half the patients complained of vomiting and headache. The storage temperature at which the oysters were kept was satisfactory and no bacterial pathogens were grown from the oyster and stool specimens. Electron microscopy revealed two distinct parvovirus-like particles in stool specimens, one of which was identified as Norwalk virus. Serological studies by immune electron microscopy showed the development of antibodies to the Norwalk-like particle by seven out of 10 patients. Confirmatory studies by radioimmunoassay showed a significant rise in antibody titre to Norwalk virus in seven patients.
大约60人在达尔文的一家酒店参加了一场圣诞晚宴，晚宴菜单上有天然牡蛎。在食用牡蛎的28人中，有25人出现食物中毒症状——发病率为89%。参加晚宴的60人中有44人接受了调查。潜伏期和病程约为36小时。100%的患者出现腹泻，88%和80%的患者分别出现绞痛和恶心。一半的患者抱怨有呕吐和头痛症状。牡蛎的储存温度令人满意，从牡蛎和粪便标本中未培养出细菌病原体。电子显微镜检查在粪便标本中发现了两种不同的细小病毒样颗粒，其中一种被鉴定为诺如病毒。免疫电子显微镜血清学研究显示，10名患者中有7名产生了针对诺如样颗粒的抗体。放射免疫测定的验证性研究显示，7名患者针对诺如病毒的抗体滴度显著升高。
