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环氧化酶抑制增强抗原诱导的气管收缩

Enhancement of antigen-induced tracheal contraction by cyclooxygenase inhibition.

作者信息

Burka J F, Paterson N A

出版信息

Adv Prostaglandin Thromboxane Res. 1980;8:1755-8.

PMID:6769322
Abstract

Enhancement of allergic tracheal constriction and contraction of the trachea by AA in the presence of cyclooxygenase inhibitors may reflect diversion of AA metabolism from the cyclooxygenase pathway.

摘要

在存在环氧化酶抑制剂的情况下，花生四烯酸（AA）增强过敏性气管收缩以及气管的收缩，这可能反映了花生四烯酸代谢从环氧化酶途径的转向。

相似文献

1
Enhancement of antigen-induced tracheal contraction by cyclooxygenase inhibition.环氧化酶抑制增强抗原诱导的气管收缩
Adv Prostaglandin Thromboxane Res. 1980;8:1755-8.
2
Studies on the role of arachidonic acid metabolites in airways contraction induced in vitro by antigen and calcium ionophore A23187.花生四烯酸代谢产物在抗原和钙离子载体A23187体外诱导气道收缩中作用的研究
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The response and sensitivity to histamine of respiratory tissues from normal and ovalbumin-sensitized guinea pigs: effects of cyclooxygenase and lipoxygenase inhibition.正常和卵清蛋白致敏豚鼠呼吸组织对组胺的反应和敏感性：环氧化酶和脂氧合酶抑制的影响
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Fetal breathing movements and inhibitors of prostaglandin synthesis.胎儿呼吸运动与前列腺素合成抑制剂
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Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.5-脂氧合酶抑制剂对抗抗原诱导的豚鼠离体气管收缩作用
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The effect of mixed inhibitors of cyclo-oxygenase and lipoxygenase on the indomethacin-induced hyper-reactivity in the isolated trachea of the pig.环氧化酶和脂氧化酶混合抑制剂对消炎痛诱导的猪离体气管高反应性的影响。
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Effects of cyclooxygenase inhibitors and PGI2 on the adrenergic contractions of isolated rabbit arteries.环氧化酶抑制剂和前列环素对离体兔动脉肾上腺素能收缩的影响。
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Evidence for lipoxygenase pathway involvement in allergic tracheal contraction.脂氧合酶途径参与过敏性气管收缩的证据。
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Study of the mechanisms of action of sodium meclofenamic acid (Meclomen) a "double inhibitor" of the arachidonic acid cascade.甲氯芬那酸钠（甲氯灭酸）——一种花生四烯酸级联反应的“双重抑制剂”的作用机制研究
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引用本文的文献

1
Allergen tachyphylaxis of guinea pigs in vivo; a prostaglandin E mediated phenomenon?豚鼠体内变应原速发耐受；一种由前列腺素E介导的现象？
Naunyn Schmiedebergs Arch Pharmacol. 1981;317(4):351-6. doi: 10.1007/BF00501318.
2
Prostaglandins and the control of airways responses to histamine in normal and asthmatic subjects.前列腺素与正常人和哮喘患者气道对组胺反应的控制
Thorax. 1983 Mar;38(3):188-94. doi: 10.1136/thx.38.3.188.
3
Prostaglandins and the lung.前列腺素与肺
Lung. 1986;164(2):65-77. doi: 10.1007/BF02713630.
4
Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity.膳食多不饱和脂肪酸对支气管超敏反应和高反应性实验模型中气管组胺能和胆碱能反应性的影响。
Agents Actions. 1987 Dec;22(3-4):223-30. doi: 10.1007/BF02009050.