γ射线辐照的恙虫病免疫原：残留、可复制立克次氏体的分析
Gamma-irradiated scrub typhus immunogens: analysis for residual, replicating rickettsiae.
作者信息
Eisenberg G H, Osterman J V, Stephenson E H
出版信息
Infect Immun. 1980 Apr;28(1):295-7. doi: 10.1128/iai.28.1.295-297.1980.
Abstract
Scrub typhus immunogens that received inadequate gamma radiation contained residual, viable rickettsiae. The presence of these organisms in the host was masked by the rapid immune response elicited by the large number of inactivated rickettsiae. Transfer of homogenized spleen cells from immunized mice to normal syngeneic recipients provided a sensitive technique for the detection of these viable, replicating organisms.
摘要
接受γ辐射剂量不足的恙虫病免疫原含有残留的活立克次体。大量灭活立克次体引发的快速免疫反应掩盖了宿主体内这些生物体的存在。将免疫小鼠的脾细胞匀浆转移到同基因正常受体中，为检测这些存活且能复制的生物体提供了一种灵敏的技术。
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