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在无持续免疫抑制情况下延长胰岛异种移植存活时间。

Prolongation of islet xenograft survival without continuous immunosuppression.

作者信息

Lacy P E, Davie J M, Finke E H

出版信息

Science. 1980 Jul 11;209(4453):283-5. doi: 10.1126/science.6770465.

DOI:10.1126/science.6770465
PMID:6770465
Abstract

The survival of isolated rat islets transplanted into diabetic mice was prolonged markedly by maintaining the rat islets in vitro at 24 degrees C for 7 days before transplantation and administering to the recipients a single injection of antiserum to mouse and rat lymphocytes shortly before transplantation.

摘要

将分离的大鼠胰岛移植到糖尿病小鼠体内,若在移植前将大鼠胰岛于24摄氏度体外保存7天,并在移植前不久给受体单次注射抗小鼠和大鼠淋巴细胞抗血清,其存活时间会显著延长。

相似文献

1
Prolongation of islet xenograft survival without continuous immunosuppression.在无持续免疫抑制情况下延长胰岛异种移植存活时间。
Science. 1980 Jul 11;209(4453):283-5. doi: 10.1126/science.6770465.
2
Induction of tolerance to islet xenografts in a concordant rat-to-mouse model.在大鼠到小鼠的协同模型中诱导对胰岛异种移植物的耐受性。
Diabetes. 1994 Jan;43(1):16-23. doi: 10.2337/diab.43.1.16.
3
Low-temperature culture of human islets or in vivo treatment with L3T4 antibody produces a marked prolongation of islet human-to-mouse xenograft survival.人胰岛的低温培养或用L3T4抗体进行体内治疗可显著延长胰岛人对小鼠异种移植的存活时间。
Proc Natl Acad Sci U S A. 1987 Nov;84(22):8080-4. doi: 10.1073/pnas.84.22.8080.
4
Prolongation of culture-isolated neonatal islet xenografts without immunosuppression.
Transplantation. 1983 Jul;36(1):6-11. doi: 10.1097/00007890-198307000-00002.
5
Pancreatic islet transplantation. Induction of graft acceptance by ultraviolet irradiation of donor tissue.胰岛移植。通过对供体组织进行紫外线照射诱导移植耐受。
Ann Surg. 1984 Oct;200(4):441-50. doi: 10.1097/00000658-198410000-00005.
6
Control of streptozotocin diabetes in Chinese hamsters by cultured mouse islet cells without immunosuppression: a preliminary report.
J Surg Res. 1980 Jan;28(1):77-85. doi: 10.1016/0022-4804(80)90086-4.
7
Prolongation of intrasplenic islet xenograft survival.延长脾内胰岛异种移植的存活时间。
Am J Pathol. 1982 Apr;107(1):1-5.
8
Ultraviolet ray direct irradiation of pancreatic islets before transplantation.移植前对胰岛进行紫外线直接照射。
Transplant Proc. 1994 Dec;26(6):3480-1.
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Transplantation of islet tissue in the rat.大鼠胰岛组织移植
Acta Endocrinol Suppl (Copenh). 1976;205:257-81.
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Immunomodulation and fish-to-mouse islet xenograft survival.免疫调节与鱼到小鼠胰岛异种移植存活
Transplant Proc. 1994 Dec;26(6):3489.

引用本文的文献

1
Islet Culture/Preservation Before Islet Transplantation.胰岛移植前的胰岛培养/保存。
Cell Med. 2015 Aug 26;8(1-2):25-9. doi: 10.3727/215517915X689047. eCollection 2015 Dec 17.
2
Induction of Pancreatic Islet Graft Acceptance: The Role of Antigen Presenting Cells.诱导胰岛移植耐受:抗原呈递细胞的作用
Transplant Sci. 1992 Apr;2(1):34-38.
3
Prevention of core cell damage in isolated islets of Langerhans by low temperature preconditioning.低温预处理预防分离的胰岛核心细胞损伤。
World J Gastroenterol. 2005 Jan 28;11(4):545-50. doi: 10.3748/wjg.v11.i4.545.
4
Induction of immune unresponsiveness to concordant islet xenografts by intrahepatic preimmunization and transient immunosuppression.通过肝内预免疫和短暂免疫抑制诱导对协同胰岛异种移植的免疫无反应性。
J Clin Invest. 1994 Mar;93(3):1312-4. doi: 10.1172/JCI117088.
5
Evidence for major histocompatibility complex restriction in transplantation immunity.移植免疫中主要组织相容性复合体限制的证据。
Proc Natl Acad Sci U S A. 1982 Jan;79(1):171-4. doi: 10.1073/pnas.79.1.171.
6
Influence of culturing on the survival of major histocompatibility complex-compatible and -incompatible thyroid grafts in rats.培养对大鼠主要组织相容性复合体相容和不相容甲状腺移植物存活的影响。
J Exp Med. 1983 Jan 1;157(1):348-52. doi: 10.1084/jem.157.1.348.
7
Demonstration of active tolerance in maintenance of established islet of Langerhans allografts.已建立的胰岛同种异体移植维持中主动耐受的证明。
Proc Natl Acad Sci U S A. 1982 Jul;79(13):4153-5. doi: 10.1073/pnas.79.13.4153.
8
Prolongation of intrasplenic islet xenograft survival.延长脾内胰岛异种移植的存活时间。
Am J Pathol. 1982 Apr;107(1):1-5.
9
Prolongation of murine islet allograft survival by pretreatment of islets with antibody directed to Ia determinants.用针对Ia决定簇的抗体预处理胰岛可延长小鼠胰岛同种异体移植的存活时间。
Proc Natl Acad Sci U S A. 1981 Aug;78(8):5156-9. doi: 10.1073/pnas.78.8.5156.
10
Pancreas and islet transplantation. I. Experimental studies.胰腺和胰岛移植。I. 实验研究。
Diabetologia. 1981 Mar;20(3):161-85. doi: 10.1007/BF00252624.