Oliven A, Taitelman U, Zveibil F, Bursztein S
Thorax. 1980 Mar;35(3):181-5. doi: 10.1136/thx.35.3.181.
In 10 patients undergoing ventilation, venous admixture was measured at different values of positive end-expiratory pressure (PEEP). The measurements were performed at the level of fractional inspired oxygen (FIO2) at which each patient was ventilated, and at FIO2=1. In patients ventilated at FIO2 between 0.21 and 0.3 venous admixture was not modified by PEEP, while in patients ventilated with FIO2 between 0.4 and 0.6, venous admixture decreased significantly (p less than 0.01). With FIO2=1, increased PEEP produced a reduction in venous admixture in all cases (p less than 0.05). These observations suggest that in patients similar to ours, PEEP does not reduce venous admixture at low levels of FIO2 (0.21--0.3), and the observed reduction with PEEP at FIO2=1 may be misinterpreted.
在10例接受通气治疗的患者中，在不同的呼气末正压（PEEP）值下测量静脉混合血。测量在每个患者通气时的吸入氧分数（FIO2）水平以及FIO2 = 1时进行。在FIO2为0.21至0.3之间通气的患者中，PEEP未改变静脉混合血，而在FIO2为0.4至0.6之间通气的患者中，静脉混合血显著降低（p小于0.01）。当FIO2 = 1时，所有病例中增加PEEP都会使静脉混合血减少（p小于0.05）。这些观察结果表明，在与我们的患者相似的患者中，低水平FIO2（0.21 - 0.3）时PEEP不会降低静脉混合血，并且在FIO2 = 1时观察到的PEEP降低可能会被误解。
