Gerald B, Sebes J I, Langston J W
AJR Am J Roentgenol. 1980 Jun;134(6):1209-12. doi: 10.2214/ajr.134.6.1209.
Cerebral angiograms were performed in 14 children with sickle cell disease and clinical findings of cerebral infarction. The angiogram was normal in four patients. Ten patients had abnormalities in the carotid artery or its branches. The internal carotid artery was stenosed or occluded usually with bilateral disease. The anterior and middle cerebral arteries were involved in nine patients and branch occlusion was frequent. The posterior fossa arteries were not involved in these patients. The risk of angiography is low if appropriate precautions are taken. In these patients the indications for arteriography were to evaluate the effects of hypertransfusion therapy on cerebrovascular disease.
对14例患有镰状细胞病且有脑梗死临床表现的儿童进行了脑血管造影。4例患者的血管造影结果正常。10例患者的颈动脉或其分支存在异常。颈内动脉通常双侧病变，出现狭窄或闭塞。大脑前动脉和大脑中动脉在9例患者中受累，分支闭塞很常见。后颅窝动脉未累及这些患者。如果采取适当的预防措施，血管造影的风险较低。在这些患者中，动脉造影的指征是评估换血疗法对脑血管疾病的影响。
