氟、锶、乙二胺四乙酸、蔗糖和安替比林在骨中的跨毛细血管交换与潴留
Transcapillary exchange and retention of fluoride, strontium, EDTA, sucrose, and antipyrine in bone.
作者信息
Lemon G J, Davies D R, Hughes S P, Bassingthwaighte J B, Kelly P J
出版信息
Calcif Tissue Int. 1980;31(2):173-81. doi: 10.1007/BF02407178.
Abstract
The extractions of 85Sr2+, 18F-, sucrose-14C, EDTA-51Cr, and antipyrine-14C in bone were determined by the multiple indicator-dilution method. Fluoride and strontium extractions were 18 to 70% during a single transcapillary passage, and those of EDTA and sucrose were from 11 to 59%, whereas extraction of antipyrine was 87%. Injections of 85Sr2+ and 18F- made when perfusion was done alternately with blood and plasma resulted in similar fractional extractions. When flow and extraction were measured simultaneously, extraction was related inversely to flow.
摘要
采用多指示剂稀释法测定了85Sr2+、18F-、蔗糖-14C、乙二胺四乙酸-51Cr和安替比林-14C在骨中的摄取量。在单次跨毛细血管通过过程中，氟化物和锶的摄取量为18%至70%，乙二胺四乙酸和蔗糖的摄取量为11%至59%，而安替比林的摄取量为87%。当用血液和血浆交替进行灌注时注射85Sr2+和18F-，得到了相似的分数摄取量。当同时测量血流量和摄取量时，摄取量与血流量呈负相关。
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