Werner H, Krasemann C, Kandler R, Wandmacher G
MMW Munch Med Wochenschr. 1980 Apr 25;122(17):633-6.
In comparative in vitro studies, broad spectrum penicillins and cephalosporins showed a relatively weak action in the range of beta-lactamase-positive bacteroides species (B. fragilis, B. thetaiotamicron) bacteroidaceae activity being otherwise good. Clindamycin was more effective against bacteroides species than against bacteria of the fusobacterium-sphaerophorus group. Metronidazole, however, showed no gap in its efficacy against bacteroidaceae, peptococcaceae and clostridium spp. with the exception of Propionibacterium acnes. The substance is therefore suitable alone and in combination for the chemotherapy of anaerobic infections.20
在比较性体外研究中，广谱青霉素和头孢菌素对β-内酰胺酶阳性拟杆菌属物种（脆弱拟杆菌、多形拟杆菌）显示出相对较弱的作用，而对其他拟杆菌科的活性良好。克林霉素对拟杆菌属物种的作用比对具核梭杆菌-球形梭杆菌菌群的细菌更有效。然而，甲硝唑对拟杆菌科、消化球菌科和梭菌属（除痤疮丙酸杆菌外）的疗效没有差异。因此，该物质单独使用或联合使用均适用于厌氧菌感染的化疗。20
