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1
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Antimicrob Agents Chemother. 1982 Aug;22(2):332-3. doi: 10.1128/AAC.22.2.332.
2
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4
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5
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6
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7
In vitro activity of rifaximin, metronidazole and vancomycin against Clostridium difficile and the rate of selection of spontaneously resistant mutants against representative anaerobic and aerobic bacteria, including ammonia-producing species.利福昔明、甲硝唑和万古霉素对艰难梭菌的体外活性以及对包括产氨菌在内的代表性厌氧和需氧菌自发耐药突变体的选择率。
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9
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J Infect Dis. 1975 Feb;131(2):182-5. doi: 10.1093/infdis/131.2.182.

引用本文的文献

1
Antibacterial effects of niridazole: its effect on microaerophilic campylobacter.
Infection. 1984 Jan-Feb;12(1):36-9. doi: 10.1007/BF01641023.
2
In vitro susceptibilities of 40 Campylobacter fetus subsp. jejuni strains to niridazole and metronidazole.40株空肠弯曲菌胎儿亚种对硝唑咪和甲硝唑的体外敏感性
Antimicrob Agents Chemother. 1984 Jan;25(1):145-6. doi: 10.1128/AAC.25.1.145.
3
Antibacterial activities of nitrothiazole against Campylobacter jejuni and Campylobacter coli.硝噻唑对空肠弯曲菌和结肠弯曲菌的抗菌活性。
Antimicrob Agents Chemother. 1984 Oct;26(4):498-500. doi: 10.1128/AAC.26.4.498.
4
Single dose prophylaxis with metronidazole in infants during abdominal surgery: a pharmacokinetic study.婴儿腹部手术期间甲硝唑单剂量预防用药：一项药代动力学研究。
Eur J Clin Pharmacol. 1986;29(5):625-8. doi: 10.1007/BF00635904.
5
Susceptibility of Campylobacter species to niridazole.弯曲杆菌属对硝唑咪的敏感性。
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6
Effect of different nitroheterocyclic compounds on aerobic, microaerophilic, and anaerobic bacteria.不同硝基杂环化合物对需氧菌、微需氧菌和厌氧菌的影响。
Antimicrob Agents Chemother. 1986 Nov;30(5):679-83. doi: 10.1128/AAC.30.5.679.
7
Antibacterial activity of GO 10213, a nitroimidazole derivative.硝基咪唑衍生物GO 10213的抗菌活性
Antimicrob Agents Chemother. 1986 May;29(5):953-4. doi: 10.1128/AAC.29.5.953.
8
Antimicrobial effects of niridazole on Gardnerella vaginalis.
Infection. 1987 Mar-Apr;15(2):128. doi: 10.1007/BF01650215.
9
Susceptibility of Campylobacter species to metronidazole, its bioactive metabolites and tinidazole.
Infection. 1987 Nov-Dec;15(6):457-8. doi: 10.1007/BF01647235.
10
Antibacterial activities of the antiparasitic drugs nifurtimox and benznidazole.抗寄生虫药物硝呋替莫和苯硝唑的抗菌活性。
Antimicrob Agents Chemother. 1989 Mar;33(3):404-5. doi: 10.1128/AAC.33.3.404.

本文引用的文献

1
Bacteriostatic and bactericidal activities of 24 antimicrobial agents against Campylobacter fetus subsp. jejuni.24种抗菌剂对空肠弯曲菌胎儿亚种的抑菌和杀菌活性。
Antimicrob Agents Chemother. 1980 Jul;18(1):118-21. doi: 10.1128/AAC.18.1.118.
2
Antibacterial effects of niridazole. I. Effect on infection of mice with Salmonella typhimurium.硝唑尼特的抗菌作用。I. 对鼠伤寒沙门氏菌感染小鼠的影响。
Chemotherapy. 1982;28(2):143-52. doi: 10.1159/000238069.
3
Differentiation of enteropathogenic Campylobacter.肠道致病性弯曲杆菌的鉴别
J Clin Pathol. 1980 Nov;33(11):1122. doi: 10.1136/jcp.33.11.1122.
4
Relative importance of bacterial and mammalian nitroreductases for niridazole mutagenesis.细菌和哺乳动物硝基还原酶在硝唑诱变中的相对重要性。
Cancer Res. 1980 Dec;40(12):4599-605.
5
[Metronidazole sensitivity of anaerobes. A comparison with other chemotherapeutics (author's transl)].厌氧菌对甲硝唑的敏感性。与其他化疗药物的比较（作者译）
MMW Munch Med Wochenschr. 1980 Apr 25;122(17):633-6.
6
[The spectrum of antibacterial activity of metronidazole].[甲硝唑的抗菌活性谱]
Zentralbl Bakteriol Orig. 1970;213(2):258-62.
7
Metabolism of niridazole in various species, including man.
Ann N Y Acad Sci. 1969 Oct 6;160(2):544-57. doi: 10.1111/j.1749-6632.1969.tb15874.x.
8
Chemistry of schistosomicides.血吸虫病治疗药物的化学
Ann N Y Acad Sci. 1969 Oct 6;160(2):519-29. doi: 10.1111/j.1749-6632.1969.tb15871.x.
9
Bactericidal activity of five antimicrobial agents against Bacteroides fragilis.五种抗菌剂对脆弱拟杆菌的杀菌活性。
J Infect Dis. 1972 Jul;126(1):104-7. doi: 10.1093/infdis/126.1.104.
10
Salmonella typhimurium infection in mice treated with niridazole.用硝唑咪治疗的小鼠感染鼠伤寒沙门氏菌。
J Med Microbiol. 1970 Aug;3(3):361-5. doi: 10.1099/00222615-3-3-361.

硝唑尼特和甲硝唑对厌氧及微需氧菌的体外比较活性

Comparative in vitro activities of niridazole and metronidazole against anaerobic and microaerophilic bacteria.

作者信息

Hof H, Sticht-Groh V, Müller K M

出版信息

Antimicrob Agents Chemother. 1982 Aug;22(2):332-3. doi: 10.1128/AAC.22.2.332.

DOI:10.1128/AAC.22.2.332
PMID:6927288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC183735/
Abstract

In vitro susceptibilities of anaerobic bacteria (Bacteroides spp., Fusobacterium spp., Clostridium spp., and Peptococcus sp.) and of Campylobacter jejuni and C. coli to niridazole and metronidazole were determined. The minimum inhibitory concentrations for niridazole ranged from 0.0037 to 1.0 microgram/ml and, for metronidazole, from 0.25 to 128 micrograms/ml.

摘要

测定了厌氧菌（拟杆菌属、梭杆菌属、梭菌属和消化球菌属）以及空肠弯曲菌和大肠弯曲菌对硝唑咪和甲硝唑的体外敏感性。硝唑咪的最低抑菌浓度范围为0.0037至1.0微克/毫升，甲硝唑的最低抑菌浓度范围为0.25至128微克/毫升。