Stigmar G, Crawford J S, Ward C M, Thomson H G
Am J Ophthalmol. 1978 Jun;85(6):806-13. doi: 10.1016/s0002-9394(14)78109-7.
The major findings in a study of 51 infants and children with infantile hemangioma of the eyelid were as follows: Visual complications occurred in 27 patients. The most common complications were amblyopia (in 22) and strabismus (in 17). Amblyopia of 6/60 (20/200) or less was probably caused by stimulus-deprivation, but amblyopia in the range of 6/30 (20/100) to 6/12 (20/40) was likely caused by anisometropia or strabismus. Eyelid occlusion of six months or more invariably resulted in amblyopia of 6/60 (20/200) or less. Occlusion for even one month carried a risk of amblyopia. Each child must be considered individually for therapy, which must be started as early as possible. Patients should receive careful follow-up from the beginning to prevent severe amblyopia. For difficult cases, we need more efficacious, safe methods to induce regression of these tumors.
一项针对51例患有眼睑婴儿血管瘤的婴幼儿的研究主要发现如下：27例患者出现视觉并发症。最常见的并发症是弱视（22例）和斜视（17例）。视力为6/60（20/200）或更低的弱视可能由剥夺性因素引起，但视力在6/30（20/100）至6/12（20/40）范围内的弱视可能由屈光参差或斜视引起。眼睑遮盖六个月或更长时间必然会导致视力为6/60（20/200）或更低的弱视。即使遮盖一个月也有导致弱视的风险。每个孩子都必须进行个体化治疗，且治疗必须尽早开始。患者从一开始就应接受仔细的随访，以预防严重弱视。对于疑难病例，我们需要更有效、安全的方法来促使这些肿瘤消退。
