Mirtallo J M, Schneider P J, Ruberg R L
JPEN J Parenter Enteral Nutr. 1980 May-Jun;4(3):300-2. doi: 10.1177/014860718000400311.
As a result of the common usage of albumin in total parenteral nutrition (TPN) solutions at The Ohio State University Hospitals, a review of the use of this product was performed. Albumin therapy in 18 patients was evaluated using prospective criteria. Therapy was considered appropriate if the serum albumin level was less than or equal to 3.0 g%. Using these criteria, 12 of 18 patients (67%) received albumin in the TPN solution. Of these 12 patients, 7 received albumin unnecessarily. During the 3-week review, a total of 168 vials of 50 ml, 25% albumin (2100 g) were administered to patients with serum albumin concentrations greater than 3.0/100 ml at a cost of $6,014. Over a year, this could mean over $100,00 in costs which could be eliminated. Criteria for use of albumin in malnourished patients receiving TPN are not well established. This study demonstrated that developing simple criteria for the prospective review of albumin in TPN solutions and using them to monitor albumin therapy closely, can result in very significant cost savings to patients receiving TPN.
由于俄亥俄州立大学医院在全胃肠外营养（TPN）溶液中普遍使用白蛋白，因此对该产品的使用情况进行了审查。采用前瞻性标准对18例患者的白蛋白治疗进行了评估。如果血清白蛋白水平小于或等于3.0 g%，则认为治疗是合适的。根据这些标准，18例患者中有12例（67%）在TPN溶液中接受了白蛋白治疗。在这12例患者中，有7例不必要地接受了白蛋白治疗。在为期3周的审查期间，共向血清白蛋白浓度大于3.0/100 ml的患者施用了168瓶50 ml、25%的白蛋白（2100 g），费用为6014美元。一年下来，这可能意味着超过10万美元的费用可以消除。在接受TPN的营养不良患者中，使用白蛋白的标准尚未明确确立。这项研究表明，制定简单的标准用于前瞻性审查TPN溶液中的白蛋白，并使用这些标准密切监测白蛋白治疗，可以为接受TPN的患者节省非常可观的费用。
