Schell L M, Agarwal S S, Blumberg B S, Levy H, Bennett P H, Laughlin W S, Martin J P
Am J Phys Anthropol. 1978 Jul;49(1):111-7. doi: 10.1002/ajpa.1330490117.
In order to help define the boundaries of the distribution of the albumin variants Naskapi and Mexico which are polymorphic among several American Indian groups, we examined sera from Micmac, Mohawk, Northwest River Naskapi, Omaha and Apache Indians, and from Aleuts and Eskimos. Sera from a total of 1,524 individuals were examined. Using a cellulose acetate membrane electrophoretic system with Tris-Citric acid at pH 5.4 we were able to distinguish normal albumin and both variants in the same run. Naskapi and Mexico variants were absent from Aleut, Eskimo, Micmac, Mohawk and Omaha samples. The albumin Naskapi variant was present in an allele frequency of 0.03 in the Naskapi Indian sample. Albumin variants Naskapi and Mexico were found in the Apache sample at frequencies of 0.016 and 0.037, respectively. This report supersedes that previously published by Schell and Agarwal ('76). Generally, within an area there is a correspondence between changes in the frequency of albumin variants and changes in the ethnic background and history of the area's populations. At the same time, when viewing widely separated areas, relationships between distant groups based on linguistic and cultural similarities are paralleled on a biologic level by the distribution of normal albumin and variant albumins.
为了帮助界定白蛋白变异体纳斯卡皮型和墨西哥型的分布界限，这两种变异体在几个美洲印第安人群体中呈多态性，我们检测了米克马克人、莫霍克人、西北河纳斯卡皮人、奥马哈人和阿帕奇印第安人以及阿留申人和爱斯基摩人的血清。总共检测了1524人的血清。使用pH值为5.4的 Tris - 柠檬酸纤维素醋酸膜电泳系统，我们能够在同一次电泳中区分正常白蛋白和两种变异体。阿留申人、爱斯基摩人、米克马克人、莫霍克人和奥马哈人的样本中不存在纳斯卡皮型和墨西哥型变异体。在纳斯卡皮印第安人的样本中，白蛋白纳斯卡皮型变异体的等位基因频率为0.03。在阿帕奇人的样本中发现白蛋白变异体纳斯卡皮型和墨西哥型的频率分别为0.016和0.037。本报告取代了 Schell 和 Agarwal（1976年）之前发表的报告。一般来说，在一个区域内，白蛋白变异体频率的变化与该区域人群的种族背景和历史变化之间存在对应关系。同时，当观察相距遥远的区域时，基于语言和文化相似性的不同群体之间的关系在生物学层面上与正常白蛋白和变异白蛋白的分布情况相平行。
