金不会改变II型胶原诱导性关节炎大鼠的关节炎、体液或细胞反应。
Gold does not alter the arthritic, humoral, or cellular responses in rats with type II collagen-induced arthritis.
作者信息
McCune W J, Trentham D E, David J R
出版信息
Arthritis Rheum. 1980 Aug;23(8):932-6. doi: 10.1002/art.1780230809.
PMID:6773531
Abstract
We assessed the effects of administration of gold sodium thiomalate on the clinical and immunologic manifestations of type II collagen-induced arthritis in rats. Injections of varying doses of gold did not alter these parameters significantly. Thus, there was no evidence in this animal model that gold possesses either antiinflammatory or immunosuppressive properties.
摘要
我们评估了硫代苹果酸金钠给药对大鼠II型胶原诱导性关节炎的临床和免疫表现的影响。注射不同剂量的金并未显著改变这些参数。因此，在这个动物模型中没有证据表明金具有抗炎或免疫抑制特性。
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