Allo antibodies in partially silent Rh phenotypes. Evidence for a possibly new high frequency Rh antigen.

Seven sera from 4 D -- --, 2 Dc -- and 1 DIV(C) -- immunized women were studied through extensive absorption-elution and coagglutination tests against a panel of common and depressed or deleted Rh phenotypes. A separable anti-e was regularly present in all sera together with an anti-Ee antibody which often showed stronger reactivity with e antigen. A possibly new anti-public Rh antibody was further separated in the serum from a D -- -- individual. The corresponding antigen is expressed on common, DIV(C) -- and depressed Rh phenotypes used, and is absent from Dc --, D -- -- and Rh null cells.