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The influence of pH on th electrophysiological effects of lidocaine in guinea pig ventricular myocardium.

作者信息

Grant A O, Strauss L J, Wallace A G, Strauss H C

出版信息

Circ Res. 1980 Oct;47(4):542-50. doi: 10.1161/01.res.47.4.542.

DOI:10.1161/01.res.47.4.542
PMID:6773697
Abstract
摘要

相似文献

1
The influence of pH on th electrophysiological effects of lidocaine in guinea pig ventricular myocardium.pH对利多卡因在豚鼠心室肌电生理效应的影响。
Circ Res. 1980 Oct;47(4):542-50. doi: 10.1161/01.res.47.4.542.
2
pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium.pKa不能预测利多卡因和W6211对豚鼠心室肌钠通道阻滞的pH增强作用。
J Pharmacol Exp Ther. 1986 Jul;238(1):159-66.
3
PH-Dependent effects of quinidine on the kinetics of dV/dtmax in guinea pig ventricular myocardium.奎尼丁对豚鼠心室肌最大dV/dt动力学的pH依赖性影响。
Circ Res. 1982 Feb;50(2):210-7. doi: 10.1161/01.res.50.2.210.
4
Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium.
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5
Evidence for a specific receptor site for lidocaine, quinidine, and bupivacaine associated with cardiac sodium channels in guinea pig ventricular myocardium.豚鼠心室肌中与心脏钠通道相关的利多卡因、奎尼丁和布比卡因特异性受体位点的证据。
Circ Res. 1985 Apr;56(4):496-506. doi: 10.1161/01.res.56.4.496.
6
Influence of buffers on dV/dtmax recovery kinetics with lidocaine in myocardium.缓冲液对心肌中利多卡因所致dV/dtmax恢复动力学的影响。
Am J Physiol. 1985 Sep;249(3 Pt 2):H663-71. doi: 10.1152/ajpheart.1985.249.3.H663.
7
Two components of use-dependent block of Na+ current by disopyramide and lidocaine in guinea pig ventricular myocytes.
Circ Res. 1991 Mar;68(3):653-61. doi: 10.1161/01.res.68.3.653.
8
Competitive inhibition of cardiac sodium channels by aprindine and lidocaine studied using a maximum upstroke velocity of action potential in guinea pig ventricular muscles.使用豚鼠心室肌动作电位的最大上升速度研究阿普林定和利多卡因对心脏钠通道的竞争性抑制作用。
J Pharmacol Exp Ther. 1987 Jun;241(3):1065-71.
9
[Effects of lidocaine and its metabolite, monoethylglycine xylidide (MEGX), on transmembrane action potentials in guinea-pig papillary muscles].[利多卡因及其代谢产物单乙基甘氨酸二甲苯酰胺(MEGX)对豚鼠乳头肌跨膜动作电位的影响]
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Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker.RSD921 一种新型钠离子通道阻滞剂的药理学和毒理学活性。
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Effects of Na+ channel blockers on the restitution of refractory period, conduction time, and excitation wavelength in perfused guinea-pig heart.
钠通道阻滞剂对豚鼠离体心脏不应期、传导时间及兴奋波长恢复的影响
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Br J Clin Pharmacol. 2010 May;69(5):427-42. doi: 10.1111/j.1365-2125.2010.03629.x.
5
Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials.丙吡胺与心脏钠通道相互作用的动力学:在正常静息电位下从开放通道快速解离。
J Membr Biol. 1993 Nov;136(2):199-214. doi: 10.1007/BF02505764.
6
Use-dependent block of cardiac sodium channels by quaternary derivatives of lidocaine.
Pflugers Arch. 1984 Feb;400(2):121-9. doi: 10.1007/BF00585029.
7
Lidocaine block of cardiac sodium channels.利多卡因对心脏钠通道的阻滞作用。
J Gen Physiol. 1983 May;81(5):613-42. doi: 10.1085/jgp.81.5.613.
8
Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?有机钙通道阻滞剂D600是在心肌细胞膜内侧还是外侧发挥作用?
Pflugers Arch. 1982 Jun;393(4):287-91. doi: 10.1007/BF00581411.
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Electrophysiological interactions between quinidine-lidocaine and quinidine-phenytoin in guinea-pig papillary muscle.豚鼠乳头肌中奎尼丁-利多卡因与奎尼丁-苯妥英钠之间的电生理相互作用。
Naunyn Schmiedebergs Arch Pharmacol. 1985 Dec;331(4):369-75. doi: 10.1007/BF00500822.
10
Effects of the novel antiarrhythmic compound TR 2985 (ropitoin) on action potentials of different mammalian cardiac tissues.新型抗心律失常化合物TR 2985(罗匹托因)对不同哺乳动物心脏组织动作电位的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1988 Mar;337(3):316-22. doi: 10.1007/BF00168845.