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[注射用阿片类成瘾者的肝炎类型(作者译)]

[Types of hepatitis in parenteral opiate addicts (author's transl)].

作者信息

Brückner O, Alexander M, Klinge O

出版信息

MMW Munch Med Wochenschr. 1980 Jul 18;122(29):1063-6.

PMID:6774237
Abstract

Fifty drug addicts with parenteral heroin abuse and tentative diagnosis of acute hepatitis were examined by means of biochemical and serological tests and by liver biopsy. Diagnosis of acute hepatitis was confirmed in 23 patients. 12 patients were examined by liver biopsy a second time 2 months to 18 months later, 3 patients underwent liver biopsy three times. In 80% of the patients markers of hepatitis B (HBsAg, anti-HBs and anti-HBc) were found in the sera. There is some evidence of not only hepatitis B, but also hepatitis non-A, non-B in parenteral drug addicts leading to protracted forms of acute hepatitis and chronic hepatitis.

摘要

对50名有静脉注射海洛因滥用史且初步诊断为急性肝炎的吸毒者进行了生化、血清学检测及肝活检。23例患者确诊为急性肝炎。12例患者在2个月至18个月后接受了第二次肝活检,3例患者接受了三次肝活检。80%的患者血清中发现了乙肝标志物(乙肝表面抗原、乙肝表面抗体和乙肝核心抗体)。有证据表明,静脉注射吸毒者不仅感染了乙肝,还感染了非甲非乙型肝炎,导致急性肝炎和慢性肝炎的迁延不愈。

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