Tiesler E, Ronald H
Z Orthop Ihre Grenzgeb. 1980;118(3):320-3. doi: 10.1055/s-2008-1053512.
The level of Ciclacillin in serum, bone, and muscle was determined in 58 patients, subjected to bone surgery. 50 to 120 minutes after application, the drug concentration in bone was many times higher than in serum.
对58例接受骨手术的患者测定了血清、骨骼和肌肉中环青霉素的水平。给药后50至120分钟,骨骼中的药物浓度比血清中的高许多倍。