Bentue-Ferrer D, van den Driessche J, Duval J
Ann Endocrinol (Paris). 1980 May-Jun;41(3):203-14.
The authors have evaluated the influence of epimestrol on several parameters: pituitary thymidine kinase in immature male rats, FSH and LH contents of pituitary and plasma in immature male and mature female rats, oestrous cycle of female rats. The results are compared with those obtained with clomiphene and cyclofenil. Epimestrol, as well as clomiphene, although at a lesser degree modifies gonadotropins levels; in contrast to clomiphene, in the pituitary thymidine kinase test epimestrol shows an oestrogenic potency but not an anti-oestrogenic one. More over it induces a vaginal cells cornification. These data suggest that epimestrol could be efficient in inducing pregnancy.
未成熟雄性大鼠垂体中的胸苷激酶、未成熟雄性大鼠和成熟雌性大鼠垂体及血浆中的促卵泡激素（FSH）和促黄体生成素（LH）含量、雌性大鼠的发情周期。将结果与使用克罗米芬和环芬尼所获得的结果进行比较。表美雌醇与克罗米芬一样，虽然程度较轻，但会改变促性腺激素水平；与克罗米芬不同的是，在垂体胸苷激酶试验中，表美雌醇显示出雌激素活性而非抗雌激素活性。此外，它会诱导阴道细胞角化。这些数据表明表美雌醇在诱导怀孕方面可能有效。
