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A comparison of assay methods for pregnancy specific beta 1 glycoprotein (SP-1).

作者信息

Ho P C, Jones W R

出版信息

Aust N Z J Obstet Gynaecol. 1980 May;20(2):109-12. doi: 10.1111/j.1479-828x.1980.tb00106.x.

DOI:10.1111/j.1479-828x.1980.tb00106.x
PMID:6774704
Abstract

Three methods were compared for the assay of pregnancy specific beta 1 glycoprotein (SP-1): radical immunodiffusion (RID), electroimmunodiffusion (EID) and radioimmunoassay (RIA). There was a significant correlation between EID and RIA. A lower, but still significant correlation was found between EID and RID, but wide discrepancies were seen in some cases. This finding suggests heterogeneity of SP-1 molecule(s). The data indicate that EID is the method of choice for assay of SP-1 after the tenth week of pregnancy, while the more sensitive RIA should be reserved for use before that stage.

摘要

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