Lin M T, Chandra A, Chern Y F, Tsay B L
Experientia. 1980 Sep 15;36(9):1077-8. doi: 10.1007/BF01965979.
At ambient temperatures (Ta) of both 8 and 22 degrees C, intraventricular administration of TRH (10-80 microgram) produced a dose-dependent hypothermia in rats. The hypothermia was due to both decreased metabolic heat production and cutaneous vasodilatation. In contrast, at 30 degrees C Ta, TRH increased metabolic heat production (due to behavioral excitation) and led to hyperthermia.
在8摄氏度和22摄氏度的环境温度（Ta）下，向大鼠脑室内注射促甲状腺激素释放激素（TRH，10 - 80微克）会产生剂量依赖性体温过低。体温过低是由于代谢产热减少和皮肤血管舒张所致。相比之下，在30摄氏度的环境温度下，促甲状腺激素释放激素会增加代谢产热（由于行为兴奋）并导致体温过高。
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