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Effects of phenobarbital, pregnenolone-16 alpha-carbonitrile, and 3-methylcholanthrene pretreatments on the distribution of NADPH-cytochrome c (P-450) reductase within the liver lobule.

作者信息

Taira Y, Greenspan P, Kapke G F, Redick J A, Baron J

出版信息

Mol Pharmacol. 1980 Sep;18(2):304-12.

PMID:6775183
Abstract
摘要

相似文献

1
Effects of phenobarbital, pregnenolone-16 alpha-carbonitrile, and 3-methylcholanthrene pretreatments on the distribution of NADPH-cytochrome c (P-450) reductase within the liver lobule.
Mol Pharmacol. 1980 Sep;18(2):304-12.
2
Pregnenolone-16alpha-carbonitrile-inducible cytochrome P450 in rat liver.孕烯醇酮-16α-腈诱导的大鼠肝脏细胞色素P450
Res Commun Chem Pathol Pharmacol. 1976 Nov;15(3):553-62.
3
The effect of phenobarbital, 3-methylcholanthrene, and pregnenolone-16 alpha-carbonitrile on the N-demethylation and O-de-ethylation of [6-H3]ethylmorphine.苯巴比妥、3-甲基胆蒽及孕烯醇酮-16α-腈对[6-H³]乙基吗啡N-去甲基化和O-去乙基化的影响。
Drug Metab Dispos. 1981 Sep-Oct;9(5):483-4.
4
Aryl and aniline hydroxylases in rat nuclear membranes after pretreatment with pregnenolone 16alpha-carbonitrile, phenobarbital and methylcholanthrene.经孕烯醇酮16α-腈、苯巴比妥和甲基胆蒽预处理后大鼠核膜中的芳基和苯胺羟化酶
Experientia. 1975 Jul 15;31(7):778-9. doi: 10.1007/BF01938459.
5
The effect of phenobarbital, 3-methylcholanthrene, 3,4-benzpyrene, and pregnenolone-16 alpha-carbonitrile on microsomal heme oxygenase and splenic cytochrome P-450.苯巴比妥、3-甲基胆蒽、3,4-苯并芘和孕烯醇酮-16α-腈对微粒体血红素加氧酶和脾细胞色素P-450的影响
Arch Biochem Biophys. 1974 Jan;160(1):274-8. doi: 10.1016/s0003-9861(74)80034-2.
6
The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver.糖皮质激素受体对于类固醇诱导细胞色素P - 4502B至关重要，但对于小鼠肝脏中药物或类固醇诱导CYP3A或P - 450还原酶并非如此。
Drug Metab Dispos. 2000 Mar;28(3):268-78.
7
Immunohistochemical localization of cytochrome P-450a in liver sections from untreated rats and rats treated with phenobarbital or 3-methylcholanthrene.细胞色素P - 450a在未处理大鼠以及用苯巴比妥或3 -甲基胆蒽处理的大鼠肝脏切片中的免疫组织化学定位。
Drug Metab Dispos. 1983 Jul-Aug;11(4):339-43.
8
Effects of microsomal enzyme inducers on carrier-mediated transport systems in isolated rat hepatocytes.微粒体酶诱导剂对分离的大鼠肝细胞中载体介导转运系统的影响。
J Pharmacol Exp Ther. 1979 Mar;208(3):381-5.
9
Differential effects of microsomal enzyme-inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2.微粒体酶诱导化学物质对大鼠有机阴离子转运体OATP1和OATP2肝脏表达的差异影响。
Hepatology. 2001 Jun;33(6):1469-78. doi: 10.1053/jhep.2001.25088.
10
Effects of clophen A50, 3-methylcholanthrene, pregnenolone-16 alpha-carbonitrile, and phenobarbital on the hepatic microsomal cytochrome P-450-dependent monooxygenase system in rainbow trout, Salmo gairdneri, of different age and sex.氯芬A50、3-甲基胆蒽、孕烯醇酮-16α-腈和苯巴比妥对不同年龄和性别的虹鳟（Salmo gairdneri）肝脏微粒体细胞色素P-450依赖性单加氧酶系统的影响。
Toxicol Appl Pharmacol. 1980 Jul;54(3):420-30. doi: 10.1016/0041-008x(80)90169-6.

引用本文的文献

1
Induction by Phenobarbital of Phase I and II Xenobiotic-Metabolizing Enzymes in Bovine Liver: An Overall Catalytic and Immunochemical Characterization.苯巴比妥诱导牛肝中 I 相和 II 相异源生物代谢酶：全面的催化和免疫化学特征。
Int J Mol Sci. 2022 Mar 24;23(7):3564. doi: 10.3390/ijms23073564.
2
Zonation of hepatic cytochrome P-450 expression and regulation.肝细胞色素P-450表达与调控的区域化
Biochem J. 1998 Jan 1;329 ( Pt 1)(Pt 1):17-35. doi: 10.1042/bj3290017.
3
NADP-dependent dehydrogenases in rat liver parenchyma. III. The description of a liponeogenic area on the basis of histochemically demonstrated enzyme activities and the neutral fat content during fasting and refeeding.
大鼠肝实质中的NADP依赖性脱氢酶。III. 根据组织化学显示的酶活性及禁食和再喂食期间的中性脂肪含量对一个脂肪生成区域的描述。
Histochemistry. 1981;72(4):579-615. doi: 10.1007/BF00493277.
4
Fluorescence-microscopic measurement of intracellular cytochrome P-450 enzyme activity (ethoxyresorufin O-de-ethylation) in unfixed liver section.在未固定的肝脏切片中进行细胞色素P-450酶活性（乙氧试卤灵O-脱乙基化）的荧光显微镜测量。
Biochem J. 1983 Apr 15;212(1):15-24. doi: 10.1042/bj2120015.
5
Liver injuries induced by cyclochlorotine isolated from Penicillium islandicum.由冰岛青霉分离出的环氯素所诱导的肝损伤。
Arch Toxicol. 1984 Mar;55(1):39-46. doi: 10.1007/BF00316584.
6
A quantitative histochemical study of NADPH-ferrihemoprotein reductase activity.NADPH-高铁血红蛋白还原酶活性的定量组织化学研究。
Histochem J. 1986 Jul;18(7):364-70. doi: 10.1007/BF01675217.
7
Induction potential of fluconazole toward drug-metabolizing enzymes in rats.氟康唑对大鼠药物代谢酶的诱导潜力。
Antimicrob Agents Chemother. 1990 Mar;34(3):402-8. doi: 10.1128/AAC.34.3.402.
8
Heterogeneity of rat liver parenchyma in cholesterol 7 alpha-hydroxylase and bile acid synthesis.大鼠肝实质在胆固醇7α-羟化酶及胆汁酸合成方面的异质性
Biochem J. 1991 May 15;276 ( Pt 1)(Pt 1):73-7. doi: 10.1042/bj2760073.
9
Postnatal changes in sublobular distribution of NADPH-cytochrome P-450 reductase in rat liver.大鼠肝脏中NADPH-细胞色素P-450还原酶小叶下分布的产后变化
Histochem J. 1992 Dec;24(12):957-63. doi: 10.1007/BF01046501.