[Practical and theoretical considerations in blood group serology of red cells (author's transl)].

Between 1949 and 1979 approximately 1.2 million blood samples were examined and the observed immune antibodies as well as natural occurring irregular antibodies were analysed. The difference of the antigenic strength of red cell markers was determined and the significance of automatic blood grouping discussed. A significant decrease of anti-D antibodies underlines the success of the anti-D-IgG-prophylaxis. Clerical errors and serological failures in a 30 year period of investigations are shown. Recommendations to avoid errors are presented.