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链霉菌对4-氯苯胺的甲酰化和乙酰化作用

Formylation and acetylation of 4-chloroaniline by a Streptomyces sp.

作者信息

Russel S, Bollag J M

出版信息

Acta Microbiol Pol. 1977;26(1):59-64.

PMID:67755
Abstract

4-Chloroaniline was metabolized in a liquid growth medium by a Streptomyces sp. which was isolated from soil. After 60 gours of incubation the aniline had disappeared and several metabolites could be detected by thin layer chromatographic analysis. 4-Chloroformylaniline and 4-chloroacetanilide were identified as products. The formation of a formylanilide by the actinomycete indicates a new mechanism of microbial aniline transformation.

摘要

4-氯苯胺在一种从土壤中分离出的链霉菌属菌株作用下,于液体生长培养基中发生代谢。培养60小时后,苯胺消失,通过薄层色谱分析可检测到几种代谢产物。已鉴定出产物为4-氯甲酰苯胺和4-氯乙酰苯胺。该放线菌形成甲酰苯胺表明了微生物转化苯胺的一种新机制。

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Formylation and acetylation of 4-chloroaniline by a Streptomyces sp.链霉菌对4-氯苯胺的甲酰化和乙酰化作用
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