采用间接免疫荧光法检测宫颈分泌物中的抗淋球菌IgA：作为诊断试验的评估
Detection of antigonococcal IgA in cervical secretions by indirect immunofluorescence: an evaluation as a diagnostic test.
作者信息
McMillan A, McNeillage G, Young H, Bain S S
出版信息
Br J Vener Dis. 1980 Aug;56(4):223-6. doi: 10.1136/sti.56.4.223.
Abstract
Using an indirect immunofluorescent-antibody method, antigonococcal IgA was detected in the cervical secretions of 56 (72%) of 78 women with untreated gonorrhoea but in only 25 (5%) of 490 non-infected women. The low sensitivity--comparable to that of Gram-stain microscopy--the expense, and the laboriousness of the test militate against its use as a routine diagnostic procedure.
摘要
采用间接免疫荧光抗体法，在78例未经治疗的淋病女性患者中，有56例（72%）的宫颈分泌物检测到抗淋球菌IgA，而在490例未感染女性中，仅有25例（5%）检测到。该检测方法灵敏度低（与革兰氏染色显微镜检查相当）、费用高且操作繁琐，不利于将其用作常规诊断程序。
相似文献
1
Detection of antigonococcal IgA in cervical secretions by indirect immunofluorescence: an evaluation as a diagnostic test.采用间接免疫荧光法检测宫颈分泌物中的抗淋球菌IgA：作为诊断试验的评估
Br J Vener Dis. 1980 Aug;56(4):223-6. doi: 10.1136/sti.56.4.223.
2
Secretory antibody response of the cervix to infection with Neisseria gonorrhoeae.宫颈对淋病奈瑟菌感染的分泌性抗体反应。
Br J Vener Dis. 1979 Aug;55(4):265-70. doi: 10.1136/sti.55.4.265.
3
[Detection of antibodies to Neisseria gonorrhoeae in cervicovaginal secretion and in serum].[宫颈阴道分泌物和血清中淋病奈瑟菌抗体的检测]
Z Hautkr. 1988 Nov 15;63(11):897-8, 905-6.
4
Secretory IgA antibody responses to Neisseria gonorrhoeae in the genital secretions of infected females.感染女性生殖道分泌物中针对淋病奈瑟菌的分泌型IgA抗体反应。
J Infect Dis. 1976 Feb;133(2):113-25. doi: 10.1093/infdis/133.2.113.
5
Evaluation of a direct immunofluorescence test for diagnosing gonorrhoea.用于诊断淋病的直接免疫荧光试验的评估。
J Clin Pathol. 1985 Oct;38(10):1142-5. doi: 10.1136/jcp.38.10.1142.
6
Antibodies to Neisseria gonorrhoeae: a study of the urethral exudates of 232 men.
J Infect Dis. 1979 Jul;140(1):89-95. doi: 10.1093/infdis/140.1.89.
7
Immunofluorescent antibody test for diagnosis of gonorrhoea.用于淋病诊断的免疫荧光抗体试验。
J Clin Microbiol. 1975 Feb;1(2):143-6. doi: 10.1128/jcm.1.2.143-146.1975.
8
Antigonococcal IgA in gonorrhoea.淋病中的抗淋球菌 IgA
Lancet. 1978 Mar 11;1(8063):557. doi: 10.1016/s0140-6736(78)90584-6.
9
Serum immunoglobulin response in uncomplicated gonorrhoea.单纯性淋病中的血清免疫球蛋白反应。
Br J Vener Dis. 1979 Feb;55(1):5-9. doi: 10.1136/sti.55.1.5.
10
Detection of Neisseria gonorrhoeae antigen by a solid-phase enzyme immunoassay.用固相酶免疫测定法检测淋病奈瑟菌抗原。
Br J Vener Dis. 1982 Dec;58(6):359-62. doi: 10.1136/sti.58.6.359.
本文引用的文献
1
Identification of Neisseria gonorrhoeae by means of fluorescent antibody technique.用荧光抗体技术鉴定淋病奈瑟菌。
Acta Pathol Microbiol Scand. 1967;70(4):613-29. doi: 10.1111/j.1699-0463.1967.tb01330.x.
2
Secretory IgA antibodies in the urethral exudate of men with uncomplicated urethritis due to Neisseria gonorrhoeae.因淋病奈瑟菌导致的非复杂性尿道炎男性患者尿道分泌物中的分泌型IgA抗体。
J Infect Dis. 1973 Jan;127(1):99-101. doi: 10.1093/infdis/127.1.99.
3
An indirect fluorescent-antibody technique for study of uncomplicated gonorrhea. II. Selection and characterization of the strain of Neisseria gonorrhoeae used as antigen.一种用于研究单纯性淋病的间接荧光抗体技术。II. 用作抗原的淋病奈瑟菌菌株的选择与鉴定
J Infect Dis. 1973 Jan;127(1):77-83. doi: 10.1093/infdis/127.1.77.
4
Studies on the quantitation of immunoglobulin in human intestinal secretions.人体肠道分泌物中免疫球蛋白定量研究。
Gut. 1973 Aug;14(8):616-26. doi: 10.1136/gut.14.8.616.
5
Serologic testing for gonorrhea.淋病的血清学检测。
Sex Transm Dis. 1977 Jan-Mar;4(1):27-31. doi: 10.1097/00007435-197701000-00009.
6
Secretory IgA antibody responses to Neisseria gonorrhoeae in the genital secretions of infected females.感染女性生殖道分泌物中针对淋病奈瑟菌的分泌型IgA抗体反应。
J Infect Dis. 1976 Feb;133(2):113-25. doi: 10.1093/infdis/133.2.113.
7
Indirect fluorescence test for the detection of anti-gonoccocal antibodies.用于检测抗淋球菌抗体的间接荧光试验。
Br J Vener Dis. 1975 Feb;51(1):28-30. doi: 10.1136/sti.51.1.28.
8
Serum immunoglobulin response in uncomplicated gonorrhoea.单纯性淋病中的血清免疫球蛋白反应。
Br J Vener Dis. 1979 Feb;55(1):5-9. doi: 10.1136/sti.55.1.5.
9
Effect of local infection and oral contraception on immunoglobulin levels in cervical mucus.局部感染和口服避孕药对宫颈黏液中免疫球蛋白水平的影响。
Infect Immun. 1975 Feb;11(2):215-21. doi: 10.1128/iai.11.2.215-221.1975.
10
Secretory antibody response of the cervix to infection with Neisseria gonorrhoeae.宫颈对淋病奈瑟菌感染的分泌性抗体反应。
Br J Vener Dis. 1979 Aug;55(4):265-70. doi: 10.1136/sti.55.4.265.
Zotero 插件