用固相酶免疫测定法检测淋病奈瑟菌抗原。
Detection of Neisseria gonorrhoeae antigen by a solid-phase enzyme immunoassay.
作者信息
Aardoom H A, de Hoop D, Iserief C O, Michel M F, Stolz E
出版信息
Br J Vener Dis. 1982 Dec;58(6):359-62. doi: 10.1136/sti.58.6.359.
Abstract
The Gonozyme test (Abbott Laboratories) is a new enzyme immunoassay for detecting Neisseria gonorrhoeae antigens in specimens from the urethra in men and the endocervix in women. To evaluate the usefulness of the assay 249 patients were investigated. The results obtained with the immunoassay were compared with those of culture and microscopy of Gram-stained smears. The sensitivity and specificity of the test were high in men with urethritis and acceptable in different groups of women. As the sensitivity of the Gonozyme test was much higher than that of microscopy for endocervical specimens it might be useful as a rapid screening test for the detection of gonorrhoea in women.
摘要
“淋菌酶”检测（雅培实验室）是一种新型酶免疫测定法，用于检测男性尿道和女性宫颈标本中的淋病奈瑟菌抗原。为评估该检测方法的实用性，对249名患者进行了调查。将免疫测定法得到的结果与革兰氏染色涂片培养及显微镜检查的结果进行了比较。该检测在男性尿道炎患者中敏感性和特异性较高，在不同女性群体中也可接受。由于“淋菌酶”检测对宫颈标本的敏感性远高于显微镜检查，它可能作为女性淋病检测的快速筛查试验。
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