Dixit P K, Ekstrom R A
Calcif Tissue Int. 1980;32(3):195-9. doi: 10.1007/BF02408541.
A simple instrument is described which measures the breaking strength of rat bones. The apparatus yields reproducible results and is suitable for use in measuring the strength of bones from both large and small animals. Diabetic rat femurs were more fragile and required less force to break in contrast to those from diabetic rats treated with insulin or normal rats. Daily insulin treatment significantly improved the bone cortical thickness and enhanced their capacity to withstand pressure, although these did not reach the level of the normal controls. The amount of force required to break the bone appears to be related to its cortical thickness and mass.
描述了一种测量大鼠骨骼断裂强度的简单仪器。该仪器可产生可重复的结果，适用于测量大小动物骨骼的强度。与用胰岛素治疗的糖尿病大鼠或正常大鼠的股骨相比，糖尿病大鼠的股骨更脆弱，断裂所需的力更小。每日胰岛素治疗显著改善了骨皮质厚度，并增强了它们承受压力的能力，尽管这些并未达到正常对照组的水平。骨骼断裂所需的力似乎与其皮质厚度和质量有关。
