Rochant H, Testa U, Vainchenker W, Henri A, Titeux M, Tonthat H, Feuilhade F
C R Seances Acad Sci D. 1980 Sep 15;291(2):229-32.
Burst forming units (BFU-E) from the blood of eight normal adults were grown in methylcellulose culture. Follow up of i and I antigens detected by an indirect immunofluorescence technique from the 9th to the 14th day of culture revealed that i antigen expression diminished while maturation proceeded. On the contrary 1 antigen expression increased meanwhile. Nevertheless, in addition to this maturation process, expression of i antigen must be determined by a regulatory mechanism operating during erythroid stem cell differentiation since a large proportion of immature erythroblasts at the 10th day of culture do not express i antigen.
从8名正常成年人血液中获取的爆式红细胞集落形成单位（BFU-E）在甲基纤维素培养基中培养。通过间接免疫荧光技术对培养第9天至第14天检测到的i和I抗原进行随访，结果显示随着成熟过程的进行，i抗原表达减少。相反，I抗原表达同时增加。然而，除了这种成熟过程外，i抗原的表达还必须由红系干细胞分化过程中起作用的调节机制决定，因为培养第10天时，很大一部分未成熟成红细胞不表达i抗原。
