Mohr H, Hesch R D, McIntosh C H, Jüppner H
Eur J Clin Invest. 1980 Aug;10(4):317-23. doi: 10.1111/j.1365-2362.1980.tb00039.x.
The composition of human parathyroid hormone immunoreactivity in the secretory granule fraction of parathyroid hormone adenomata was investigated. Granular extracts were separated by gel filtration and the eluates assayed by radioimmunoassay and sequence specific immunoradiometric assays detecting aminoterminal and carboxyterminal activity. About half of the extracted adenomata contained fragments besides intact hormone. The fragment composition varied from adenoma to adenoma.
对甲状旁腺激素腺瘤分泌颗粒部分中人类甲状旁腺激素免疫反应性的组成进行了研究。颗粒提取物通过凝胶过滤进行分离，洗脱液通过放射免疫测定以及检测氨基末端和羧基末端活性的序列特异性免疫放射测定进行检测。大约一半的提取腺瘤除了完整的激素外还含有片段。片段组成因腺瘤而异。
