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阻塞性睡眠呼吸暂停患者皮肤表面氧分压和二氧化碳分压的连续测量

Continuous measurements of skin surface oxygen and carbon dioxide tensions in obstructive sleep apnea.

作者信息

Rowe L D, Hansen T N, Nielson D, Tooley W H

出版信息

Laryngoscope. 1980 Nov;90(11 Pt 1):1797-803. doi: 10.1288/00005537-198011000-00006.

Abstract

We have found that skin surface electrodes for continuously measuring oxygen (PSO2) and carbon dioxide (PSCO2) tensions provide reliable means of determining whether infants with apnea due to airway obstruction during sleep require treatment. Nine patients referred for evaluation of aqnea during sleep were studied. In 6 patients with PSO2 less than 50 torr during sleep, the hypoxic episodes were clearly associated with partial or total airway occlusion as judged by increasing respiratory effort without concomitant airflow. PSCO2 was found to increase during the episodes of obstruction in all 6 patients. These patients were treated with 1. tracheotomy, 2. tonsillectomy and adenoidectomy in 2 patients, 3. bilateral mandibular condylotomies, 4. pharyngeal flap release, and 5. discontinuing topical nasal decongestants. After treatment, all had decreased hypoxia, hypercarbia, or airway obstruction. Two of the remaining 3 patients had no alterations of PSO2 or PSCO2 associated with airway obstruction during sleep. The third exhibited hypoxia and hypercarbia secondary to central apnea. We conclude, therefore, that continuous monitoring of skin surface oxygen and carbon dioxide tensions is useful in evaluating children with obstructive sleep apnea.

摘要

我们发现,用于连续测量氧气(PSO2)和二氧化碳(PSCO2)分压的皮肤表面电极,为确定睡眠期间因气道阻塞而出现呼吸暂停的婴儿是否需要治疗提供了可靠的方法。对9名因睡眠呼吸暂停前来评估的患者进行了研究。在6名睡眠期间PSO2低于50托的患者中,低氧发作明显与部分或完全气道阻塞相关,这可通过呼吸努力增加而无伴随气流来判断。在所有6名患者中,发现阻塞发作期间PSCO2会升高。这些患者接受了以下治疗:1.气管切开术;2. 2名患者接受扁桃体切除术和腺样体切除术;3.双侧下颌髁突截骨术;4.咽瓣松解术;5.停用局部鼻减充血剂。治疗后,所有患者的低氧、高碳酸血症或气道阻塞情况均有所减轻。其余3名患者中的2名在睡眠期间未出现与气道阻塞相关的PSO2或PSCO2变化。第三名患者表现为中枢性呼吸暂停继发的低氧和高碳酸血症。因此,我们得出结论,连续监测皮肤表面氧气和二氧化碳分压有助于评估阻塞性睡眠呼吸暂停患儿。

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