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微囊化胰岛作为生物人工内分泌胰腺

Microencapsulated islets as bioartificial endocrine pancreas.

作者信息

Lim F, Sun A M

出版信息

Science. 1980 Nov 21;210(4472):908-10. doi: 10.1126/science.6776628.

DOI:10.1126/science.6776628
PMID:6776628
Abstract

Single implantation of microencapsulated islets into rats with streptozotocin-induced diabetes corrected the diabetic state for 2 to 3 weeks. The microencapsulated islets remained morphologically and functionally intact throughout long-term culture studies lasting over 15 weeks.

摘要

将微囊化胰岛单次植入链脲佐菌素诱导的糖尿病大鼠体内,可使糖尿病状态得到纠正,持续2至3周。在长达15周以上的长期培养研究中,微囊化胰岛在形态和功能上均保持完整。

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Microencapsulated islets as bioartificial endocrine pancreas.微囊化胰岛作为生物人工内分泌胰腺
Science. 1980 Nov 21;210(4472):908-10. doi: 10.1126/science.6776628.
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Macroencapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months.大封装猪胰岛可在长达6个月的时间内纠正灵长类动物的诱导性糖尿病。
Adv Exp Med Biol. 2015;865:157-70. doi: 10.1007/978-3-319-18603-0_10.

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