丙戊酸钠治疗精神分裂症：一些生化关联
Sodium valproate in schizophrenia: some biochemical correlates.
作者信息
Lautin A, Angrist B, Stanley M, Gershon S, Heckl K, Karobath M
出版信息
Br J Psychiatry. 1980 Sep;137:240-4. doi: 10.1192/bjp.137.3.240.
PMID:6777010
Abstract
Sodium valproate given in doses of 750-3000 mg daily to eight schizophrenic patients produced a qualitatively similar increase in symptoms in five. CSF showed no significant change in gamma-amino-butyric acid or methoxy hydroxyphenyl glycol, but homovanillic acid increased non-significantly in five patients.
摘要
对8名精神分裂症患者每日给予750 - 3000毫克丙戊酸钠治疗，其中5名患者的症状出现了性质类似的加重。脑脊液中γ-氨基丁酸或甲氧基羟基苯乙二醇无显著变化，但5名患者的高香草酸有非显著性增加。
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