狒狒抗癌胚抗原血清的评估。
Evaluation of baboon antiserum to carcinoembryonic antigen.
作者信息
Haagensen D E, Cox C E, Dilley W G, Hensley M, Murdoch J, Newman E S, Wells S A
出版信息
Clin Chem. 1980 Dec;26(13):1787-90.
PMID:6777083
Abstract
The common baboon (Papio), immunized with carcinoembryonic antigen (CEA), was found to form specific-site antibodies for CEA. The baboon antiserum does not recognize colon carcinoma antigen-III, but does demonstrate similar ionic strength effects to those previously described for goat antisera to the CEA-specific site(s). Baboon specific-site antibody for CEA can be used for radioimmunoassay of CEA in plasma and gives similar results to the commercial (Roche) goat anti-CEA.
摘要
用癌胚抗原（CEA）免疫普通狒狒（Papio）后，发现其能形成针对CEA的特定位点抗体。狒狒抗血清不能识别结肠癌抗原III，但在离子强度效应方面与先前描述的针对CEA特定位点的山羊抗血清类似。狒狒针对CEA的特定位点抗体可用于血浆中CEA的放射免疫测定，结果与市售（罗氏）山羊抗CEA类似。
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