Typing Mycobacterium tuberculosis with mycobacteriophage Bo4.

Mycobacteriophage Bo4 grown on the indicator host strain Mycobacterium fortuitum SN203 was restricted and modified by Mycobacterium tuberculosis H37Rv. Phage Bo4.Rv was restricted and modified by the alternate host SN 203. M. tuberculosis strain Myc 1025 was described as a r-m-isolate. By using the mycobacterial prototype strains for phage typing wild M. tuberculosis isolates, it was demonstrated that only the modified phage Bo4.H37Rv was a potential typing phage.