用分枝杆菌噬菌体Bo4对结核分枝杆菌进行分型

Typing Mycobacterium tuberculosis with mycobacteriophage Bo4.

作者信息

Jones W D

出版信息

J Gen Virol. 1980 Aug;49(2):319-22. doi: 10.1099/0022-1317-49-2-319.

Abstract

Mycobacteriophage Bo4 grown on the indicator host strain Mycobacterium fortuitum SN203 was restricted and modified by Mycobacterium tuberculosis H37Rv. Phage Bo4.Rv was restricted and modified by the alternate host SN 203. M. tuberculosis strain Myc 1025 was described as a r-m-isolate. By using the mycobacterial prototype strains for phage typing wild M. tuberculosis isolates, it was demonstrated that only the modified phage Bo4.H37Rv was a potential typing phage.

摘要

在指示宿主菌株偶然分枝杆菌SN203上生长的分枝杆菌噬菌体Bo4受到结核分枝杆菌H37Rv的限制和修饰。噬菌体Bo4.Rv受到替代宿主SN 203的限制和修饰。结核分枝杆菌菌株Myc 1025被描述为一种限制-修饰分离株。通过使用分枝杆菌原型菌株对野生结核分枝杆菌分离株进行噬菌体分型，结果表明只有修饰后的噬菌体Bo4.H37Rv是一种潜在的分型噬菌体。