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使用偶然分枝杆菌噬菌体F-phi WJ-1来识别更多结核分枝杆菌的噬菌体类型。

Use of phage F-phi WJ-1 of Mycobacterium fortuitum to discern more phage types of Mycobacterium tuberculosis.

作者信息

Jones W D, Greenberg J

出版信息

J Clin Microbiol. 1976 Mar;3(3):324-6. doi: 10.1128/jcm.3.3.324-326.1976.

Abstract

A total of 125 strains of Mycobacterium tuberculosis from the Southeastern area of the United States was subjected to phage typing. In addition to the five major mycobacteriophages, a new phage, F-phi WJ-1, was used in the study. The results obtained with the five major phages were: type A0, 35.2%; TYPE B, 29.6%, and type C, 4.0%. The remaining 21.2% of the strains phaged typed as subgroups A1 through A6. These percentages were similar to the typing results of earlier studies. The new phage, F-phi WJ-1, subdivided each of the phage types, with the exception of type C, into two subgroups. The possible role of host modification-restriction of the phages used in phage typing of strains of M. tuberculosis is discussed.

摘要

对来自美国东南部的125株结核分枝杆菌菌株进行了噬菌体分型。除了五种主要的分枝杆菌噬菌体外,一种新的噬菌体F-phi WJ-1也用于该研究。使用五种主要噬菌体获得的结果如下:A0型,35.2%;B型,29.6%;C型,4.0%。其余21.2%的菌株被分型为A1至A6亚组。这些百分比与早期研究的分型结果相似。新噬菌体F-phi WJ-1将除C型外的每种噬菌体类型细分为两个亚组。讨论了在结核分枝杆菌菌株噬菌体分型中使用的噬菌体的宿主修饰限制的可能作用。

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本文引用的文献

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Bacteriophage typing of Mycobacterium ranae (Fortuitum). The use of unadapted and adapted phages in the development of a typing system.
Acta Pathol Microbiol Scand B Microbiol Immunol. 1974 Feb;82(1):87-93. doi: 10.1111/j.1699-0463.1974.tb02297.x.

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