Rentz R
Klin Padiatr. 1980 Sep;192(5):460-6. doi: 10.1055/s-2008-1035626.
The literature on the correlation of epilepsy and psychosis is reviewed briefly. The terms "forced normalization" and "alternative psychosis" and further the risk factors in the genesis of psychosis in epilepsy are underlined with special emphasis on childhood and adolescence. Furthermore the case of a girl aged 16.7 years is reported. This girl developed blinking fits at the age of 7 years and in 1978 at the age of 16 paranoid-hallucinatory symptoms with temporarily increasing paroxysmal potentials in the EEG following an initial depressive phase. Phenytoin and Valproate was administered. The psychotic and epileptic symptoms diminished with simultaneous amelioration of the EEG. After discharge a neuroleptic medication was added temporarily due to slight exacerbation of the psychotic symptoms. Finally risk factors of psychosis in epilepsy are considered with special respect of mental retardation and age of the patient.
本文简要回顾了关于癫痫与精神病相关性的文献。重点强调了“强制正常化”和“交替性精神病”这两个术语,以及癫痫患者发生精神病的危险因素,尤其关注儿童期和青春期。此外,还报告了一名16.7岁女孩的病例。该女孩7岁时出现眨眼发作,1978年16岁时,在经历初始抑郁期后出现偏执幻觉症状,脑电图阵发性电位暂时增加。给予苯妥英钠和丙戊酸盐治疗。精神病性和癫痫症状减轻,脑电图同时改善。出院后,由于精神病性症状略有加重,临时加用了抗精神病药物。最后,特别考虑了癫痫患者发生精神病的危险因素,涉及智力发育迟缓以及患者年龄。